The most expensive drugs sold in American pharmacies can cost as much as a luxury car — every month.

U.S. based @GoodRx is back with the latest update of the top 20 most expensive drugs in America. The list is based on patient-administered drugs, and does not include medications that must be administered by a healthcare practitioner. Prices are U.S. list price (WAC).

According to the analysis, Myalept is the most expensive out-patient prescription drug in the US in 2020 with a list price of $71,306.

Over 50% of the products are indicated for rare diseases, mostly congenital or hereditary. And surprisingly, two of the products are off-patent.

Out of the entire list, eight drugs are more expensive than they were last year.